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Win 10 is not compatible with serial port pl2303 driver solution.
Try to uninstall with the installation file, whether it can be uninstalled or not, and uninstall the line with exclamation point from the hardware manager. Unplug the TTL line. In the folder toolbar options, turn on Show Hidden Files and Show File Extensions.

From the picture, it is not supported since WIN8, so it is very likely that WIN 10 system does not support it either. It is recommended to install WINDOWS7 system, which should work normally.

Open Baidu, enter USBMASSSTORAGEDEVICE driver to search, click Search in the pop-up webpage, and select the appropriate download site to download. Unzip the downloaded driver to a new folder. Open Device Manager, right-click USBMASSSORAGEDEVICE, and select Update Driver.

Method 1: We can try to search and open the device manager. Find an incompatible device in it, right-click, click "update driver", finally select automatic search driver, and then follow the prompts to install.

Just install the latest pl2303usb-to-serial driver, which can support win7/8/ 10 and other systems. Do not connect USB before installation, and then connect USB after installation. If other USB-to-serial drivers have been installed before, be sure to uninstall them.