Trifluoroacetic acid TFA
Uses and characteristics: Polypeptide products are usually trifluoroacetate. Because trifluoroacetic acid has great biological toxicity, some experiments need to avoid this salt.
acetate fiber
Uses and characteristics: Because of the low biological toxicity of acetic acid, most medicinal peptides or cosmetic peptides are acetate. However, the acetate stability of some products is not good, so the sequence stability should be considered. ?
HCl hydrochloride
Uses and characteristics: fewer products will choose hydrochloride. Some sequences require the use of special-purpose hydrochloride. ?
Ammonium salt NH4+
Usage and characteristics: it will seriously affect the solubility and stability of the product, so it needs to be selected in order. ?
Sodium salt Na+
Uses and characteristics: usually affect the solubility and stability of products. ?
Palmer acid
Usage and characteristics: pamoate is usually used to prepare sustained-release preparations of polypeptide drugs. ?
Citrate citrate
Usage and characteristics: the biological toxicity is small, but the preparation process is complex, so it is necessary to make the production process independently according to the order.
Salicylic acid salicylate
Usage and characteristics: it affects the stability of polypeptide products and is rarely used. ?