2 Diagnosis of Down Syndrome Screening We can judge the risk value of Down Syndrome by screening Down Syndrome during pregnancy. Down's screening is a detection method to calculate the risk factors of birth defects by extracting the serum of pregnant women, detecting the concentrations of fetal protein A, chorionic gonadotropin and free estriol in maternal serum, and combining the expected date of delivery, weight, age and gestational age of pregnant women.
For Down's screening of high-risk pregnant women by amniocentesis, doctors usually suggest further examination, amniocentesis or non-invasive DNA examination. Noninvasive DNA detection does not involve uterus, but the detection accuracy is not as good as amniocentesis. Amniocentesis can confirm whether the fetus is Down's syndrome, but because it is an invasive examination, there is a miscarriage rate of five thousandths.
3 Prevention of Down syndrome At present, there is no effective prevention method for Down syndrome. The best way is for pregnant mothers to do Down's screening and terminate pregnancy before delivery after medical confirmation.
4 Down syndrome Down syndrome is mainly characterized by mental retardation, developmental retardation, special face, and often accompanied by congenital heart disease and other malformations. The specific manifestations are that the skull is relatively small and round, the distance between face and eyes is wide, the eye fissure is small, the outer corner of the eye is oblique, the tongue often sticks out of the mouth, drooling is much, the figure is short, the bone age is lagging behind, and there are still backward motor functions such as clumsy movements, uncoordinated movements and unstable gait. Male Tang Bao is infertile, while female Tang Bao may have fertility, but it is hereditary.