It polymerizes with α -tubulin to form microtubules, which are the basic structural units of many organelles and are necessary for cell reproduction processes such as mitosis, protein assembly and energy metabolism.
Indications are mainly used for the treatment of Dichromatic trematodes (gills), Benedum trematodes and marine fish cultured in fresh water.
Parasitic diseases caused by fingerling, third generation worms and myxosporidia in cultured fish.
Usage and dosage: Feed the fish with bait. Use 20g of this product per 100Kg body weight once a day for 4-7 days.
Eel diseases and treatment: the occurrence and treatment of monogenesis
The main parasitic species of Monogonimus anguillicaudatus are Dactylogyrus, Dactylogyrus and the third generation worm.
Monosomiasis is a common epidemic in eel culture, which occurs in late spring, early summer and late autumn, especially in rainy season. Due to its mechanical damage and stimulation to gill tissue, gill mucus hyperplasia and respiratory decline will affect its food intake, and even hunger strike in severe cases. Traumatic tissues are easily infected by other pathogens, such as bacteria and fungi, which will lead to the outbreak of gill rot, especially in high temperature season. Monosomiasis is often complicated with desquamation and septicemia, which will bring obstacles to the treatment of this disease.
Due to the common phenomenon of monogenesis in cultured eels, chemicals such as organophosphorus, pyrethroids and imidazole are usually used in aquaculture. The long-term and frequent use of these drugs has made pathogens resistant, and the tolerance of zooplankton in the environment to these drugs is also increasing. Trichlorfon, Dendrocalamus latiflorus and potassium permanganate commonly used in Japanese eel culture, mebendazole and albendazole used in European eel culture and American eel culture are difficult to treat these pathogens, and even if the dosage is increased to above the safe concentration of eel, it is difficult to drive out these monogeneous trematodes. However, the increase of dose will inevitably lead to stress reaction in fish, and in severe cases, it will lead to eel. In particular, mebendazole works by preventing sugar from being converted into ATP, thus blocking the energy supply of the body. Therefore, it often takes more than 36 hours for fish to react to mebendazole before poisoning symptoms appear. In addition, the toxicity of mebendazole to fish increases with the increase of water temperature, so it is easy to cause eel poisoning if fish specifications and water temperature are not considered when mebendazole is used. Mebendazole poisoning is common in eel culture in recent two years, which is mainly caused by blindly increasing the dosage of mebendazole without considering the factors such as water temperature and water quality. Due to the occurrence of poisoning, if proper detoxification treatment is not carried out, the environment will change sharply or other drugs will further stimulate eels, which will easily lead to swimming death. For the same reason, organophosphorus poisoning often occurs.
In view of the above situation, many fish medicine manufacturers and scientific research units are now conducting research on specific drugs, and have introduced some products, such as Dijun Powder, Insecticide King, Baichong Kill and Baichong Ke. However, the efficacy of these drugs in actual production and application is still unclear, and their efficacy varies significantly with different environments, so it is urgent to strengthen the research on these special therapeutic drugs and programs.