As early as the Spring and Autumn Period and the Warring States Period, there were records about the medical use of wormwood. Zhuangzi says, "The more people smoke them, the more they love them.". "On Mencius Li Lou" says: "I still have seven years of illness, and I want three years of love." It can be seen that as early as the Spring and Autumn Period, the efficacy of wormwood has been recognized.

Mencius' so-called "three-year moxa" is a further understanding of the use of wormwood. Artemisia argyi preserved for 3-5 years not only eliminates dryness, but also preserves medicinal properties, and is most suitable for moxibustion.

There is a record in Fifty-two Diseases Prescription that burning wormwood is smoked and roasted to treat hemorrhoids. Folium Artemisiae Argyi was recorded in Treatise on Febrile Diseases, and the Jiao Ai Tang mentioned in it is still a gynecological prescription for treating blood deficiency and cold stagnation and menorrhagia. Gehong's Elbow Backup Emergency Prescription in the Eastern Jin Dynasty states that "patients with moxibustion have four beds, one strong and one strong, so that they will not be infected", which is to prevent pestilence and infectious diseases by fumigation with mugwort leaves.

the famous doctor's Bielu first recorded mugwort leaves as medicine: "mugwort leaves are bitter, slightly warm and nontoxic. The main moxibustion can be used to treat all diseases, and it can be used as a decoction to stop diarrhea, vomiting blood, sores on the lower part, women leaking blood, benefiting yin qi, promoting granulation, sheltering from the wind and cold, and making people have children. "

Su Song in the Song Dynasty mentioned in China's Book of Materia Medica that "Artemisia argyi leaves, which are old, are not out of the state, but clouds grow in the fields. Today, it is everywhere, and it is better to return to the Tao. This kind of moxibustion is especially good for all diseases. " There is also a picture of "Ming Zhou Ai Ye" in the book. Tangyin county in Anyang, Henan Province, and Ningbo in Zhejiang Province in Siming. The book was the first to put forward an authentic medicinal material that paid attention to the quality of wormwood. The Biography of Artemisia argyi is a monograph on Artemisia argyi, which describes that Artemisia argyi is "produced in Shanyang, and used for the Dragon Boat Festival to cure moxibustion diseases, which is not a small contribution".

Li Shizhen in the Ming Dynasty was a physician who greatly admired wormwood, and his praise for wormwood was endless. His book Compendium of Materia Medica did a lot of research and records on wormwood, including "wormwood leaves can cure all diseases by moxibustion", "Moxibustion can penetrate all meridians, but treating all kinds of diseases and evils, and people who are addicted to it are kang tai, and their achievements are also great" "The old man is weak in abdomen and timid in abdomen." Li Shizhen pointed out that Artemisia argyi "since its formation, it has been known as Artemisia argyi, which is the most important thing in the world. It is said that moxibustion in other places is impenetrable, while moxibustion in Artemisia argyi is straight and thorough, which is different". Artemisia argyi is an authentic medicinal material, which has been used to this day.