Humanism is a cultural phenomenon. It first appeared in Italy, especially Florence, and then gradually spread to all parts of Europe. The cultural movement laid the foundation for the development of modern culture by innovating literature, philosophy, history, science and art. In their view, medieval culture was a theological culture, with a preconceived mysterious world view, which stifled people's personality and made people mentally, physically and intellectually rigid. The only thing people could see was God's will. They demanded to rediscover man's role in historical development, affirm the value of man's will and action, and restore man's rights, including his due position before God. Early humanists praised the enterprising and optimistic spirit of the emerging commercial bourgeoisie, demanded recognition of the legitimacy of human happiness they obtained through labor, and opposed the strangulation of human happiness by asceticism. At this time, artists and thinkers put people at the center of everything in the universe and highly praised people's rationality and spirit. With the collapse of the theological system, people got rid of the shackles of religious dogma and restored their enthusiasm for the real world rationally and emotionally. After natural science got rid of the fetters of theology and astrology, man became the master of nature, and he must shoulder the new responsibility of exploring the mysteries of nature. 1492 new discoveries in the United States have broadened people's horizons. All this calls for a new era. In the final analysis, as Mirandola said, man is the creator and builder of himself.