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Candida is a conditional pathogen, and whether it will get sick after invading human body depends on the level of human immunity, the number and virulence of infected bacteria. When pregnancy, diabetes, oral contraceptives, long-term use of broad-spectrum antibiotics, corticosteroids and immunosuppressants make the body's immunity decline and change the internal environment, it is easy to induce candida infection.

The pathogenicity of Candida is related to the following factors: ① Adhesion; Adhesion is directly proportional to virulence, and Candida albicans has the strongest adhesion among Candida species. ② Two types of sexual morphology: When infected, Candida albicans is often hyphal. The virulence of mycelium type is stronger than that of yeast type; ③ Toxins: polysaccharide toxin on the surface of bacterial cells and another kind called "Candida toxin" may be pathogenic factors; ④ Cell surface components; ⑤ Extracellular enzymes: Candida albicans can produce and secrete some enzymes, such as lysophospholipase, phospholipase and extracellular acid protease (CAP). Among them, CAP is the most important. CAP can hydrolyze not only protein, but also keratin and collagen, which can promote the adhesion of Candida albicans.

Candida albicans infection first adheres to the epithelial cells of the host, and then forms an infection focus under the action of the pathogenic factors of Candida albicans mentioned above. Adhesion to epithelial cells is due to the adhesion receptors of Candida albicans on the surface of host cell membrane, namely fucose and N- acetylglucosamine. There are many kinds of adhesion mediators on the cell wall of Candida albicans, among which mannan-protein complex (M-P) and chitin are the most important ones. Chitin is a three-dimensional polymer composed of (1-3,1-6) β -glucan and N- acetylglucose. The cell wall of Candida albicans has adhesive receptors such as fibrinogen and fibronectin. These components are widely distributed in blood vessel wall, inflammation and wound healing, and have strong adhesiveness. After adhering to Candida albicans, they can bridge the adhesion between Candida albicans and host cells, making it easier for Candida albicans to adhere to and invade the host. Help me, count my life. < P > Scorpio/Xiao Niu < P > Scorpio Xiao Niu is a smart child with crazy temperament, Xiao Niu is a cautious and ordinary person, and he < P > acts. Scorpio is quite cunning and fanatical, suspicious and magical.

Scorpio bulls are quite strange, and they seem to know intuitively how to act to avoid offending the opposite

and achieve the set goals. Such people are always trying to move in a certain direction, and their momentum can leave the challengers around

far behind. It's not that Scorpio bulls seem to act in a hurry, but they are just ruthless and ascetic

trying hard to pursue what they want-that is, looking at the highest salary and the highest glory

.

What is quite special about their personality is that they always have an indescribable sense of superiority among the people around them.

Where he appears, people immediately know who is the leader of the group. This kind of people have the natural

solemnity of Scorpio and the drive of pursuing goals. They never have to consider emotional factors when making up their minds. Scorpio

Xiao Niu can understand the emotional needs, but they usually don't allow their enthusiasm to interfere with the progress of their careers.

Of course, Scorpio bulls seem to be powerful and bullying, and they must rule others. They are complacent about their ability to grasp the situation and their gift of eloquence. This kind of person often appears quite humorous and knows how to

make others laugh. However, their ego is more demanding than their consciousness, and they are not good at laughing at themselves.

Scorpio bulls are enviable objects. People will easily envy them and often try to hide the efforts of Scorpio bulls by violent and despicable means. However, Scorpio bulls are also tough and strong people, and will not give up easily.

Love

Scorpio bulls are attractive and powerful, and they will have many admirers. Among these people, he

tends to choose the object with beautiful appearance, and he is not interested in the exchange of intelligence, but would rather be attracted by the violent

quarrel, separation and rupture.

suitable for * * * objects

Cancer, virgin, Mojie and Pisces of the hamster match you. Xiao Ji's Cancer, Mojie or Pisces < P > are also suitable. Cancer, virgins or brown-grinders of Xiao snake will bring you happiness; Gemini, Taurus, lion and Aquarius of Xiao sheep are not. Taurus and Gemini in Laban Xiao will disappoint you, and Taurus of Xiao Monkey, Gemini of Xiao Ma or Aquarius of Xiao Hu are not suitable.

Occupation

Professions related to power attract Scorpio Xiao Niu the most, and his fluent expressive power will also attract him to participate in various performances. This kind of person has a natural performance ability. He can also arouse the masses to engage in great actions, even to launch a revolution. He seems a little crazy, so he can't be entrusted with military duties. Besides, he prefers smiling to

non-aggression. Suitable jobs include performers, actors, political leaders, teachers, writers, film directors,

drama directors, communication experts and comedians.

Famous people: drama master Liszt Berger, US Senator Robert Kennedy, movie stars Fisher and Richard Burton,

American TV presenter Johnny Carson.

Birthday password:

November 4th-a spy who incites words

People born on November 4th have the ability to stir up disputes. Their words and actions are often full of provocative meanings, and they are often leaders and valued members in family and social circles.

Many people born on this day, though conservative in attitude and plain in appearance, show their personal charm and diverse personality in their conversations. When they meet for the first time, they usually give people an impression of liveliness and sincerity, and they don't immediately show their provocative side. However, the longer we know each other, the more we can see that they are not only good at embellishing, but also can pierce the thickest retaining layer. As masters who are good at breaking through the defense line, they are very aware of other people's weaknesses or vulnerabilities. Seriously, once they start to act, it's hard for anyone to stop them, even they can't do it easily. Therefore, knowing their own shortcomings and controlling themselves will become more and more urgent in their life goals, and maintaining a positive attitude towards life should be especially kept in mind for them.

In addition, people born on November 4th also have a good sense of humor. Although sometimes it may just make people smile and stop, sometimes it will infect others and even lead to a lively atmosphere. It is precisely because of this humanistic and positive characteristic that they can quickly overcome the boundaries of race, class or religion. Even if it's just a joke or some laughter, they can relax everyone and break the rigid atmosphere. On the other hand, because they are seldom depressed, it is difficult for them to understand the negative side of others. But the most serious problem is that they often fail to realize how bad their situation is, and when the prospects are actually bleak, they still remain overly optimistic.

People born on November 4th are very attractive. They not only have the talent to persuade people, but also can turn a blind eye to others' positive criticism or cleverly avoid it. Because in their minds, they always think that sooner or later others will fully believe their views. However, in the end, they often misjudge the acceptance of others, especially when their views are extreme and the way they speak annoys others or even makes them feel annoying. A chaotic situation like this may weaken their influence.

Although people born on November 4th like to be served, they usually at least repay others with relative kindness. In fact, they can be said to be the type of overpayment, so others may take advantage of this weakness and ask too much. Even if people born today seem to have endless energy, the expectations of others will become a heavy burden for some people over a long period of time.

Women born on this day should be especially careful. As for men, they can't live without emotional nourishment, but for those who are close to them, perhaps their needs are a little too much, so we should be careful not to form the habit of dependence.

Lucky Numbers and Ruling Stars

People born on November 4th will be influenced by the numbers 4 and Uranus. People affected by the number 4 usually have their own way of dealing with things; Uranus, on the other hand, represents the ability to change instantly and unpredictable actions, which will shine even more brightly in people born on November 4. Generally speaking, people influenced by the number 4 don't pay much attention to money, so people born on November 4 also have a kind of concentration and persistence in their ideals without exception. Even so, they can't stand the psychological damage, especially when they are rejected by the group they are fully committed to. In addition, the combination of Uranus and Pluto (the dominant planet of Scorpio) also shows sexy charm.

Health

People born on November 4th are devoted in all aspects, which may cause psychological and physical stress. For this reason, it will be very important for them to limit their responsibilities and seek a quiet home as a refuge, or take a hidden vacation on a regular basis. In addition, people born today tend to ignore the warning that their health is getting worse, which is usually because they are more concerned about others. However, they should at least take basic precautions to avoid being attacked by infectious diseases. Many people born on November 4th love food so much that their appetite is amazing. Therefore, it is quite difficult for them to control their diet, and it is even more nerve-racking for women born on this day to control their weight. In any case, fear of exercise is the most effective solution.

Suggestions

Try to face life with a more neutral stance. Handle things calmly and try to control your emotions. Don't blindly pay more than you can bear, but also pay attention to your demands on others. Don't forget to carry forward your sense of humor.

Celebrity

Will Rogers is an American humorist, folklorist, stage and film actor. He is a famous legend, who famously said, "Everything that happens to others is fun", and later died in a plane crash.

Toshiyuki Nishida, a Japanese actor, is his masterpiece Dunhuang.

Robert Mapplethorpe, a controversial photographer, whose bold behavior and works triggered a heated discussion between obscene behavior and book censorship.

Art Carney is an American comedian in stage play, film and TV. In 1974, he won the Oscar for Best Actor for The Old Man and the Cat. His masterpiece is Honeymoon Travel, in which he plays the role of Norton.

Freddie Heineken, president of Heineken, the largest beer manufacturer in the Netherlands, has established a huge sales network in 15 countries around the world.

Tarot Card

The fourth card of Tarot Card, the great secret instrument, is "Emperor". His strength mainly comes from wisdom, and he rules everything in the world by it. The emperor's position is supreme, and his authority cannot be questioned. When the card face is straight, it represents strong will and stable energy; When the card is upside down, it means willfulness, tyranny and cruelty.

meditation

words or actions in which mutual trust trumps everything.

Advantages

Extremely charming, devoted and charming.

disadvantages

nosy and impractical.

I don't know whether it's accurate or not. These are all calculated by the solar calendar. Please help!

The opportunity is only for those who are prepared-the eight-year career of the little girl

Let me talk about my eight-year career in Beijing for your reference. A lot of things are very personal, and may not have a lot of reference significance. I can only say that what I said is all my own personal experience and I am completely realistic.

1. Job-hunting experience: from 1995 to 1996

I graduated from a key university in 1996, majoring in English and was assigned to work in Beijing.

because of my boyfriend, I initially targeted Beijing for job hunting. Looking for a job is still very bitter in retrospect. At that time, it was not easy to find a job. My family had nothing to do with it, and it was not easy to find a job for an English major. I was a girl. I went to Beijing to take some big unit exams, but there were no results. Later, I happened to attend an interview for an office executive in a big company with a national prefix in Beijing. I did well in the interview. I feel that if it is fair competition, it should be me. But I don't have much hope. I remember when someone asked about the salary, the other party said it was 1,3 yuan a month, the basic salary in 3 yuan, the food subsidy in 5 yuan and the bonus in 5 yuan. The company provides dormitories. At that time, I thought it would be great if I could get this job, because my parents worked all their lives and only earned more than 1 yuan a month. Can I get so much money as soon as I graduate? (At that time, my monthly living expenses in college were 3 yuan, which was good among my classmates. )

It turned out that I was very lucky. The recruiting leader really wanted to hire the right person, and he hired me without looking at anything. Although this job finally became a chicken rib, it was really welcome at that time and I was happy for a long time.

(Experience 1: Whether you can find a good job after graduation is only a phased achievement. Sometimes it's a blessing in disguise or a blessing in disguise. Many of my colleagues in this state-owned enterprise were one or two good students recommended by a department in those days and were able to enter this company. As a result, some of their classmates didn't find a good job after graduation, so they came out early and came from behind. So far, they are deeply moved. )

2. State-owned enterprises for three years, from 1996 to 1999

In July 1996, I reported to Beijing.

The company dormitory is rented from a nearby school. Tube-shaped apartment, a room of 12 square meters for three people. In winter, breath can be seen in the room. It's hot in summer, so I have to carry a bucket of water to the public toilet to deal with it.

What's worse is that people in the dormitory are not easy to get along with. Give two examples. A person likes to cook a big table of food at night and ask her good friends to eat it. After eating, I put it all on the table and went out to play. In summer, the temperature in the room is definitely above 3 degrees. Can you imagine the smell in the room if the leftovers are left like this for several hours? Either endure it or I'll have to clean it up. This happens almost two or three times a week. It's hard to imagine that people who love cooking don't like washing dishes. ) and at the weekend, she