We can think of famous quotes from Hawking in a wheelchair:
Every problem has a solution, and there is no unimaginable thing. ——Edison
The most terrifying enemy is the lack of strong belief. ——Romain Rolland
I want to seize fate by the throat. ——Beethoven
The response to imagined difficulties is not to escape or bypass them, but to face them, deal with them, and fight against them in an aggressive and wise way.
——Maxwell Maltz