It means: Throughout the ages, people who have achieved great things must not only have talents (knowledge and ability) beyond ordinary people, but also have a strong will to overcome difficulties.
It is hypocrisy to give up without fighting, and it is frivolous to be detached without suffering.
It means: you must do it yourself, don't be intimidated by difficulties, and don't shrink back in the face of difficulties. Otherwise, it is not advisable to give up or stop fighting easily on the grounds of "detachment".