Alexander studied under the famous Greek philosopher Aristotle and received Greek cultural education from an early age. He loves Greek culture and dreams of not only conquering the world, but also hellenizing it. From the age of 16, he followed his father to participate in military campaigns and learned a lot of combat techniques and military knowledge. After he succeeded to the throne, he followed the example of Greece and carried out political and military reforms: weakening the power of clan nobles, strengthening the power of monarchs, reforming the monetary system and encouraging the development of industry and commerce; A standing army, including infantry, cavalry and navy, was established. The infantry formed a dense and deep combat formation, which was called Macedonian phalanx, with heavy infantry in the middle and light infantry on both sides. Each phalanx is also equipped with heavy cavalry composed of aristocratic children, as the pioneer and flank protection of the phalanx. Through these reforms, Macedonia quickly became a military power.

In 334 BC, Alexander led 35,000 troops and 160 warships into Persia, and began the eastward expedition. At that time, the Persian Empire was extremely weak, and Alexander easily conquered Asia Minor Peninsula with a fierce offensive. In 333 BC, Alexander's army defeated the Persian army in Isu and opened the door to Syria and Phoenicia.

In 332 BC, Alexander conquered Syria and entered Egypt. He was declared "son of Amon" (king) by Egyptian priests. He called himself Pharaoh and built Alexandria at the Nile Gate to commemorate his great achievements.

In 33 1 BC, Alexander led his army to a decisive battle with the Persian army in Goga Milasi on the east bank of the Tigris River. Persia was defeated and Darius Iii fled. Alexander captured Babylon, occupied the Persian capitals of Susa and Persia, and the ancient capital of Medea, Ek Platthana. In the spring of 330 BC, Darius Iii was killed by the Ministry and the Persian Empire perished. Alexander conquered all Persia. Established the Alexander Empire across Europe, Asia and Africa, with Babylon as its capital. Its territory starts from Greece and Macedonia in the west, reaches the Indus Valley in the east, connects the first waterfall of the Nile River in the south, and reaches Yaoshashui (now the Syr Darya River) in the north.

In 327 BC, Alexander continued eastward, passing through Rest (Parthia), Aliya and Delagana, crossing the Hindu Kush Mountains and reaching Bactria (Summer) and Sogdian. In 325 BC, it invaded India and occupied the Indus Valley. He also tried to conquer the Ganges valley, but after years of long-distance fighting, the soldiers were exhausted, infected with malaria and injured by poisonous snakes, and refused to move on. In July 325 BC, Alexander had to withdraw his troops from India. In 324 BC, the Crusade ended.

In 323 BC, Alexander died suddenly, and the huge empire established by military conquest also collapsed. After a long period of melee, many independent kingdoms were formed on the original imperial map, the largest of which were Macedonia, Egypt and Seleucu, which were later destroyed by Rome.