Zuo Si's "Sandu Fu" was written in the first year of Taikang, and Bai Juyi once wrote a poem: "A seal is sparse into the valley, and Sandu Fu is reserved." At that time, the whole world was competing to copy Sandu Fu, and even the idiom "Luoyang paper is expensive" appeared to reflect the grand occasion of people competing to copy Sandu Fu. Huangfu Mi, a famous medical scientist, is known as the "originator of acupuncture". After reading it, he gave a high evaluation and preface to Sandu Fu. Zuo Si, the author of Sandu Fu, was a native of Qi and later became an important member of the literati group. Zuo Si himself is eager to learn and study hard, and his literary talent is brilliant. Although he had a high literary talent, he failed repeatedly and died in Taian the next year. He is the author of Sandu Fu, Yong Shi and some piano music. Zuo Si's Sandu Fu consists of three parts: Du Wei Fu, Wudu Fu and Shu Du Fu. Wang Mingsheng once said that in the early years of the Western Jin Dynasty, Zuo Si tried to write Sandu Fu, which was written to "eliminate Wudu and Shudu, and apply for Dewey to succeed Wei Tonger". Sandu Fu is rich in content and grand in system. Become a masterpiece of Zuo Si, a masterpiece of China history. Although there are some shortcomings, it reflects the social life in the Three Kingdoms period to a certain extent, which is of far-reaching significance to the development of China's ancient literature.