I can see that you have a strong sense of health and high vigilance in self-protection, which is a good thing! Here I want to congratulate you first! But as the saying goes, excessive sensitivity will have a negative impact on health. Rabies is mainly transmitted through illness and bite (scratch) injury of virus-carrying animals, and its secretion (most importantly saliva) pollutes the wound; People should be injected with rabies vaccine within 24 hours after being bitten (scratched) by rabid animals (or animals with rabies virus). This is not to say that they will get rabies as soon as they are bitten, but because the fatality rate of rabies is 1% and there is still no medicine to save it, so the consequences of the disease are extremely serious! This is an important reason why people have to go to the CDC to get rabies vaccine once they are bitten (scratched) by cats and dogs. The sooner the rabies vaccine is injected, the better. It is aimed at the pathogenesis of rabies. Generally, as long as it is injected within 24 hours after injury, it can make the body produce rabies virus antibodies before the outbreak of rabies virus infection, so as to effectively remove the virus and prevent the onset; Rabies virus is a pathogen with large particles and bullet-like shape, which has not been isolated from human sweat so far. To sum up, signing with a gel pen will definitely not be infected by rabies virus, and friends can relax and live happily and healthily!