According to the Blood Donation Law of People's Republic of China (PRC) (1998), Quality Management Standard of Blood Stations (2006), Management Measures of Blood Stations (2006) and Health Examination Requirements for Blood Donors (20 12), it is illegal for blood station staff to collect blood excessively and frequently before collecting blood.

We have three principles in recruiting blood donors:

The first is the voluntary principle: blood donors donate blood voluntarily, without any external coercion or improper temptation. The voluntary principle of voluntary blood donation is the autonomy of blood donors and the implementation of the principle of informed consent.

The second is the principle of free: it shows that blood donation is a noble altruistic behavior. Blood donation is to save other people's lives. Not for your own benefit.

Third, the principle of safety: when recruiting blood donors, take all necessary measures to minimize the risks that may occur in the process of blood donation recruitment, avoid the risks that could have been avoided as much as possible, and minimize the inevitable risks.

2. Will donating 400ml blood affect your health?

1). Physiological components of blood

Blood consists of blood cells and plasma. Normal blood accounts for 7%~8% of human body weight. By calculation, a person weighing 60kg contains 4200ml to 4800ml of blood. Normally, 10% to 20% of the blood is stored in the liver, spleen, lungs and capillaries. When blood is lost, the stored blood will be released immediately and participate in blood circulation and maintenance.

2) Physiological recovery after blood donation

After blood donation, through self-regulation, the water and inorganic salts in the body penetrate into the blood vessels from the tissue fluid, and the liver accelerates the synthesis of plasma protein, and the stored blood will be released compensatory to replenish the blood volume, so the blood volume will recover after one or two hours, and the plasma protein will recover in a day or so.

Giving 200ml whole blood can reduce the average hemoglobin of 50kg normal adults by 7~8g/L, and it only takes 7~ 10 days to fully recover.

In the literature (Sun Jie, Qian Kaicheng, Wu Xiaodong et al. "Study on the Changes of Blood Cell Count before and after Blood Donation"), the blood cell count and hemoglobin value of 63 blood donors before and after blood donation were detected, and it was concluded that the blood cell count of blood donors increased rapidly after blood donation, reaching the peak at 1 h, and the blood was obviously replenished at 1 week after blood donation, so blood donation was 400 or 2000.

3. Why should we suggest and encourage blood donation of 400ml?

1). Reduce expenses

Blood bags, blood tests and blood separation all need money. Collecting a bag of 400ml blood is less than collecting two bags of 200ml blood with one blood bag, with one initial reexamination and one blood separation.

2) Reduce the risk of transfusion-transmitted diseases among recipients.

Due to the limitation of current technology, it is impossible to eliminate the window period of transfusion-transmitted diseases. Any bag of blood products has the risk of spreading transfusion-related diseases. Especially compared with other infection routes, transfusion-transmitted diseases enter the recipients through blood transfusion, with higher infection rate and faster progress of the disease. This is related to the amount of virus input and the patient's own bad condition.

Compared with two bags of blood 1U, one bag of 2U blood can reduce the risk of transfusion-transmitted diseases by half.

3). Adverse reactions of blood transfusion.

As long as clinicians who have applied for blood transfusion know, almost all adverse reactions of blood transfusion, including fever and allergy, will occur after blood transfusion. We call them transfusion complications, including adverse reactions and diseases caused by blood components themselves, foreign bodies and microbial transmission during or after blood transfusion.

Common transfusion adverse reactions include non-hemolytic febrile transfusion reaction (incidence 1/500), allergic reaction (incidence 1/20000~ 1/47000) and acute hemolytic transfusion reaction (incidence1/7000 ~/kloc) AHTR has several reasons:

(1) blood group incompatibility

(2) Type A, B and AB patients were given O whole blood.

(3) transfusion of incompatible plasma

(4) Multiple blood donors transfused blood in a short time.

(5)A2 subtype incompatibility

(6)Rh blood group incompatibility

(7) Other rare blood group is not suitable.

(8) Blood group antibodies that cannot be detected by general serological methods.

Blood group incompatibility between blood donors is an inevitable problem at present. If there is blood group incompatibility between blood donors, it is difficult to find the reason. At present, some blood group antibodies can not be detected and infused into the recipient because of negative cross-matching.

AHTR develops rapidly, and hemolysis may occur as long as 10~ 15ml incompatible blood is input. 30 ml of incompatible red blood cell transfusion will lead to the death of the recipient.

Therefore, doctors are advised not to transfuse blood to patients who can't transfuse blood, and patients who can transfuse less don't lose more. Patients who need more blood transfusion, when there are complications of blood transfusion, must observe the signs of patients and take corresponding treatment measures immediately to avoid more serious consequences.

Finally, pay tribute to the potential blood donors who are willing to donate blood and the caring people who insist on donating blood without compensation. I hope this article can answer your doubts. At the same time, as a medical staff and blood bank staff, I hope everyone can donate 400ml when the body allows, which is absolutely helpful to alleviate the pain of patients. For comrades who can't donate 400ml, it doesn't matter if they donate 200ml. They can help others and save lives. If there are mandatory staff during blood donation, report decisively to reduce this uncivilized and immoral phenomenon of blood donation recruitment. At the same time, in this case, if you refuse to sign the consent form, you can donate blood in other blood donation vehicles without suffering indignities. I believe this uncivilized phenomenon is only the behavior of a few colleagues.