What are the health regimens for high blood pressure?
Everyone has their own method of health care. What can people with high blood pressure do in life to improve their health care and truly protect themselves and keep their blood pressure stable? Well, let’s take a look now. The best health regimen for patients with high blood pressure in the article.
Health regimen for high blood pressure, actively participate in outdoor sports, and bask in the sun as necessary
Patients with high blood pressure and high-risk groups should actively participate in outdoor sports, because spending 10 minutes outdoors in the sun can lower blood pressure. Can drop by 6 mm Hg.
The healthy way to maintain high blood pressure is to talk less and listen more to reduce fluctuations in the cardiovascular system
After more than 20 years of painstaking research, medical experts at the University of Maryland in the United States have discovered that the differences between people Any interaction will have varying degrees of impact on the body, and even a casual chat about the weather can affect the cardiovascular system, especially blood pressure.
Healthy regimen for high blood pressure: Look more at blue and green, which has a magical effect in regulating blood pressure
Care magazine published in the United States suggested that patients with high blood pressure may wish to use more blue and green decorations in their homes. It has a certain effect on regulating blood pressure.
Alternate hot and cold baths repeatedly to promote blood circulation
First bath in cold water for 3 minutes, a healthy regimen for high blood pressure, then bathe in hot water for 3 minutes, repeat 7 times a day Second-rate. Helps enhance blood vessel elasticity, promote blood circulation, and is effective against high blood pressure caused by arteriosclerosis.
Eat garlic every day to easily lower blood pressure
Eating 2 to 3 cloves of garlic every day is the easiest way to lower blood pressure. One study showed that consuming 600 to 900 mg of garlic paste can lower blood pressure by an average of 11 mm of mercury.
Eat more potassium-containing foods to control blood pressure and high blood pressure activity summary
2022 high blood pressure activity summary sample (general 9 articles)
Unknowingly, one The wonderful event is over. I believe you must have a lot of experiences worth sharing. I feel it is necessary for us to summarize the event. So what does a good activity summary look like? The following is a sample article on hypertension activity summary in 2022 that I compiled for you (generally 9 articles). Welcome to read and collect.
Summary of Hypertension Activities 1
October 8, 2019 is the xxth National Hypertension Day, and this year’s publicity theme is “xx”. Because increasing public awareness is a prerequisite for preventing and controlling hypertension. In order to strengthen the publicity and education of health knowledge, improve the self-protection ability of the people, and create a social atmosphere in which everyone participates in maintaining healthy blood pressure, our center has launched a series of publicity activities. The activities are summarized as follows:
10 On the 8th, publicity was carried out in front of the unit building, hanging banners, placing publicity boards, producing 5,000 leaflets, distributing various promotional materials, broadcasting publicity knowledge on the prevention and treatment of hypertension in the lobby on the first floor of the unit, and specially inviting people from Xinmin City Qi Liwei, director of the hospital's Department of Circulatory Medicine, gave a lecture on hypertension prevention and treatment and promoted it to the city's citizens through the news media. Remind the general public: 1. Measure blood pressure regularly (for normal adults, it is recommended to measure blood pressure at least once every 2 years; for first-time patients over 35 years old, it is recommended to measure blood pressure; for people prone to hypertension, it is recommended to measure blood pressure once every six months; Those who meet the standard and live an unstable life should increase the number of times they self-test their blood pressure;) 2. Prevention of high blood pressure (keep exercising, limit salt intake, eat more vegetables and fruits, eat less fast food, limit alcohol consumption, and quit smoking).
This publicity event distributed 6,110 copies of promotional materials (5,000 leaflets on hypertension prevention and control knowledge, 300 leaflets on prevention and control of hypertension, 200 leaflets on tobacco control, 100 handbooks on tobacco control, natural 60 disaster personal protection manuals, 100 health education brochures, 100 human bird flu brochures, 100 brucellosis prevention and control knowledge brochures, 50 tobacco crime evidence brochures, and fluorosis prevention and control knowledge brochures), benefiting a total of 6,000 people, thereby improving the health literacy level of the general public.
Summary of Hypertension Activities 2
October 8, 2019 is the xxth "National Hypertension Day" in my country. The theme of this publicity activity is "xx" to effectively prevent and control high blood pressure, and improve the general public's awareness and attention to hypertension. According to the requirements of the documents of the city's Center for Disease Control and Prevention, our hospital carefully organized and conscientiously implemented it. On October 8, 10 people from the public health department of the hospital were arranged , health consultation and publicity activities with the theme "xx" were held at the entrance of the hospital and Yuezhuang Farmers Market. The purpose is to improve the general residents' understanding of the awareness rate, treatment rate and control rate of hypertension, achieve the purpose of early detection, early diagnosis and early treatment of hypertension, and promote better implementation of basic public health service projects.
By widely disseminating knowledge on the prevention and treatment of hypertension, we will further strengthen residents' health education and health promotion, improve residents' health education awareness and health level, and make residents aware of core knowledge such as "regularly going to medical institutions" to measure blood pressure. Improve the awareness rate, treatment rate, and control rate of hypertensive patients, and promote the file management of hypertensive patients, thereby reducing the incidence and mortality of cardiovascular diseases.
There were more than 120 participants in this health consultation and promotion activity. One promotion banner was hung on site, more than 160 copies of hypertension promotion materials were distributed, and more than 80 people received voluntary blood pressure measurements and health consultations. At the same time, health promotion boards were published 1 issue. Through this publicity activity, the concept of quitting smoking, limiting alcohol, and exercising appropriately will be further deeply rooted in the hearts of the people, so that the general public can take active actions to prevent and control high blood pressure and enjoy a healthy life. In addition, This activity further improved the residents' initiative in learning health knowledge and strengthened their awareness and ability to prevent and control hypertension. This activity enabled residents to deepen their understanding of hypertension and healthy lifestyles, and gain a clear understanding of how to prevent and treat hypertension. awareness. This activity has been well received by the local residents and achieved good social results.
Summary of Hypertension Activities 3
In order to improve the public awareness. To raise awareness of hypertension and enhance the public's ability to actively prevent it, on the morning of October 8, the district health and family planning department held a large-scale theme publicity event for "National Hypertension Day" in Phoenix Plaza.
This year. The theme of the publicity is "Know your blood pressure". The activity carries out health publicity with the contents of "Risk factors and early symptoms of hypertension", "Improving the early detection rate of hypertension" and "Patients' self-management knowledge" to guide everyone to do a good job in " Health measures such as "reasonable diet, moderate exercise", "healthy weight, healthy blood pressure", and "regularly measuring blood pressure and blood sugar at medical institutions" can reduce the risk of hypertension and reduce and delay the occurrence of complications.
At the event site, relevant staff of the District Center for Disease Control and Prevention distributed promotional materials on the prevention and control of hypertension, salt reduction to prevent hypertension, and key points of healthy lifestyle knowledge. Medical staff from other medical units also provided blood pressure measurements, free clinics, Health consultation services to help residents improve their awareness of hypertension prevention and treatment and further guide the people to actively develop a healthy lifestyle
Summary of hypertension activities 4
October 8 this year is. On the 13th National Hypertension Prevention and Control Day, our hospital closely focused on the publicity theme of "Healthy Weight, Healthy Blood Pressure" to carry out publicity activities on the prevention and treatment of hypertension among residents in our town. This activity is summarized as follows: < /p>
1. Organizational leadership:
The director of the information department of the hospital will be the team leader, and 4 doctors and nurses from each department of the hospital will be selected to form a publicity team to be responsible for this publicity work.
2. Clear purpose:
Through publicity and consultation activities, improve the general public’s knowledge of hypertension and how to establish a healthy lifestyle and stay away from the disease.
3. Organization and implementation:
In this publicity work, the staff of the publicity team set up two on-site consultation points at the entrance of Gaotanwei Village of Xiuxi Village Committee and the entrance of Liantang Village of Taiqian Village Committee. Received more than 300 on-site consultations from the general public, patiently answered various questions raised by them, and distributed more than 300 health prescriptions for the prevention and treatment of hypertension; dispatched 4 publicity vehicles
4. Achieved results:
This Hypertension Awareness Day event has a warm atmosphere, a wide range and a strong focus. Through this Awareness Day event, the general public can master more health knowledge, thereby encouraging them to develop a good lifestyle and hygiene. Habit.
In the future health education work, our hospital will set up more consultation points to communicate face-to-face with the masses to make the effect of the education more obvious.
Summary of Hypertension Activities 5
Every year, March and Day are the "National Hypertension Day" designated by the Ministry of Health of my country. This year marks the 16th Hypertension Day in my country. The theme is "Healthy Heartbeat, Healthy Blood Pressure." The purpose is to call on residents to improve their lifestyles, reduce salt intake, and control high blood pressure. The leaders of our hospital attach great importance to this event and require medical staff to fully understand the current situation of preventing and treating hypertension. They have carried out a lot of work around the theme of this year's "National Hypertension Day" and organized personnel around the theme from October to A publicity campaign for “National Hypertension Day” was carried out, which is summarized as follows.
1. Leaders attach great importance to diversifying publicity forms
The main leaders of the hospital organize the activities; in order to implement various tasks, they make full use of media such as radio and bulletin boards. By carrying out consultation and free clinic activities and distributing promotional materials, we produced "National Hypertension Day" consultation and free clinic banners for community health centers and outpatient clinics, and organized medical staff to conduct on-site publicity and free clinics in various communities. Prepare for the event and be responsible for taking photos, making work reports, distributing "hypertension" promotional materials, and answering questions from time to time to the visitors, answering all questions so that everyone can have a more accurate understanding of hypertension-related knowledge.
2. The theme of the activity is prominent and goes deep into the community
Our community health service center has adopted effective measures and various colorful forms to carry out a series of publicity activities to prevent and treat hypertension. During the process, the theme was continuously strengthened and relevant knowledge such as the dangers, prevention and treatment of hypertension was vigorously promoted. Improve the public's awareness of the prevention and treatment of hypertension. Through this "National Hypertension Day" publicity, the general public has a better understanding of the prevention and treatment of hypertension. It has been well received by community residents and has received good community benefits. This has greatly improved the health of the people in our region. In total, more than 1,000 copies of relevant "hypertension prevention and treatment" materials were distributed to more than 120 visitors for free blood pressure measurement, and more than 400 people were consulted by relevant people. A survey on the awareness rate of hypertension knowledge was conducted. The survey showed that before the publicity and lectures, there were 75% of people have reached 60 points or more, 25% have not reached 60 points or more, and only 15% of people over 60 years old have reached 60 points or more. Surveys after publicity and lectures show that 95% of people have reached 60 points or more. 5% of people did not reach 60 points or above, and more than 50% of people over 60 years old achieved 60 points or above.
3. On-site convenience and publicity in place
Our community health service center conducted on-site publicity and consultation activities at the Family Courtyard of No. 4 Middle School in our town from October to 2019, and distributed Relevant promotional materials to promote and introduce the background of "National Hypertension Day" and the knowledge and significance of hypertension.
This event is well received by the masses. Through the activities, the masses can further understand the harm of high blood pressure to the body, understand the benefits of a reasonable diet and moderate exercise to the body, and improve the treatment of various chronic diseases. prevention knowledge.
Summary of Hypertension Activities 6
In order to do a good job in promoting the National Hypertension Day in 20xx and further improve the health awareness and level of the general public, according to the "20xx Liaoning Province Health Education Center National Hypertension Day Publicity Activity Plan", Dandong City held a consultation and free clinic publicity activity with the theme of "Healthy Heart Rate, Healthy Blood Pressure" to improve the awareness, treatment and control rates of hypertension patients in Dandong City and achieve the goal of achieving high blood pressure. The purpose of early diagnosis and early treatment is to promote the good implementation of public health services.
The Zhen'an District Center for Disease Control and Prevention jointly participated with the township-level medical units in Zhen'an District and carried out publicity activities in front of the Changlong Business Hotel and the Changlong Market in Zhen'an District. At the same time, medical staff set up a consultation desk. Free blood pressure measurements will be taken on passers-by. Each township prevention and protection station has opened a hypertension bulletin board in the residential areas under its jurisdiction; each township health center vigorously publicizes the knowledge of hypertension prevention and treatment, so that the public understands that controlling hypertension is the entry point for the prevention and treatment of chronic diseases. Zhenxing District Center for Disease Control and Prevention, in conjunction with Zhenxing District Liudao Community Health Service Center, organized relevant professionals to hold a "Hypertension Day" publicity event in Liudao West Community, with free consultations, health knowledge lectures, and distribution of promotional materials as the main forms of activities, so that Community residents further understood common sense related to the prevention and treatment of hypertension, strengthened the public's awareness of hypertension prevention and treatment, corrected previous misunderstandings, and popularized knowledge of hypertension prevention and treatment.
The Donggang City National Billions of Farmers Health Promotion Office, Donggang City Health Bureau, Donggang City Center for Disease Control and Prevention, and Donggang City Hospital of Traditional Chinese Medicine jointly set up a consultation desk in the lobby of the Hospital of Traditional Chinese Medicine, measured blood pressure at free clinics, and distributed promotional materials. Promotional activities with the theme of "Healthy Heart Rate, Healthy Blood Pressure".
This series of activities has 9 information desks and 17 medical staff dispatched. At the same time, more than 90 free blood pressure measurements were provided for patients and accompanying persons on site, and more than 80 people answered their inquiries. 7 slogans There were 12 publicity display boards, large electronic screens were used to broadcast the publicity themes and information related to the prevention of hypertension, and more than 1,500 copies of more than 8 types of brochures, foldouts, leaflets, and book series on the prevention of hypertension were distributed. The audience reached more than 600 people.
Widely disseminate knowledge on the prevention and treatment of hypertension through activities, further strengthen residents' health education and health promotion, improve residents' health education awareness and health level, and make residents aware of core knowledge such as "regularly going to medical institutions" to measure blood pressure. , improve the awareness rate, treatment rate, and control rate of blood pressure patients, and promote hypertension file management, thereby reducing the incidence and mortality of cardiovascular diseases.
Hypertension is the most common chronic disease and the main risk factor for cardiovascular and cerebrovascular diseases. October 8 this year is my country’s xxth “National Hypertension Day”. In order to popularize the knowledge of hypertension prevention and treatment, improve the awareness rate of hypertension prevention and treatment knowledge among residents in our city, promote the cardiovascular health of residents, and effectively prevent and treat cardiovascular and cerebrovascular diseases, the center, together with the Municipal Health Education Institute and Yangshe Town Community Health Service Center, held a conference on October 8 In the morning, an on-site publicity activity for "National Hypertension Day" was carried out in Lianxin Community, Yangshe Town.
At the event site, the staff hung up promotional banners and held up high blood pressure education display boards. Residents nearby who were doing morning exercises stopped and carefully watched "How to Know and Control Blood Pressure", "How to Eat a Reasonable Diet" and other health topics Knowledge. A consultation desk was set up on site to provide on-site consultation to residents, and free blood pressure and blood sugar measurement services were provided to residents. The risk factors and prevention knowledge of hypertension were explained face-to-face to residents. The staff also provided residents with healthy cooking aprons and distributed them A health knowledge leaflet on chronic diseases such as hypertension, smoking, diabetes, and tumors was published, which was well received by the residents at the site.
Through the promotion of Hypertension Day, more residents can understand the dangers and prevention knowledge of hypertension, and strengthen residents’ awareness of proactive prevention and control of cardiovascular and cerebrovascular diseases. Residents have expressed that they will actively build a healthy life in the future. In this way, we must "lower salt, lose weight, reduce stress, quit smoking, and limit alcohol" to become a healthy and progressive Hong Kong citizen and make our work and life more exciting.
Summary of Hypertension Activities 7
1. The hospital uses electronic screens and bulletin boards to disseminate knowledge about the prevention and treatment of hypertension to incoming patients and their families.
2. On the morning of October 8, staff from the Public Health Department of our hospital came to Mazhuang Nursing Home to conduct free clinics for the elderly here. At the same time, they measured blood pressure on site, hung banners, and distributed leaflets. The prevention and treatment knowledge of hypertension was disseminated to the elderly through on-site explanations.
3. On the same day, medical staff from the Epidemic Prevention Department came to Mazhuang Village Market to promote the prevention and self-control of hypertension to the passing public by setting up an information desk, hanging banners, distributing leaflets, and accepting consultations on site. .
Through the above publicity activities, the general public has further understood the knowledge of prevention and treatment of hypertension, strengthened the public's awareness of prevention and treatment of hypertension, and improved society's awareness of hypertension. At the same time, it improves the awareness rate, treatment rate and control rate of patients with hypertension, achieves the purpose of early diagnosis and early treatment of hypertension, and promotes the good implementation of public health services.
Summary of Hypertension Activities 8
In order to do a good job in promoting the "National Hypertension Day" in 20xx and further improve the health awareness and level of the general public, according to the forwarding of the Municipal Health Bureau Notice from the General Office of the Ministry of Health, the Municipal Center for Disease Control and Prevention, and the District Center for Disease Control and Prevention on the launch of the 20xx National Hypertension Day Publicity Activities by the General Office of the Ministry of Health. On the morning of October 8, 20xx, the Dongqu Street Community Health Service Center held a consultation and free clinic promotion event with the theme of "Knowing Your Hypertension and Control Goals" at the entrance of the center. The main purpose was to increase the awareness rate of patients with hypertension in Guangzhou. , treatment rate, control rate, achieve the purpose of early diagnosis and early treatment of hypertension, and promote the good implementation of public health services.
Widely publicize the knowledge on prevention and treatment of hypertension through activities, further strengthen residents' health education and health promotion, improve residents' health education awareness and health level, and make residents aware of core knowledge such as "regularly going to medical institutions" to measure blood pressure. , improve the awareness rate, treatment rate, and control rate of blood pressure patients, and promote hypertension file management, thereby reducing the incidence and mortality of cardiovascular diseases.
There were more than 400 participants in this free clinic consultation activity, more than 300 copies of hypertension and various health knowledge promotional materials were distributed, and 40 files were established. There were 79 patient signatures who came for consultation, blood pressure measurement, height and weight measurement. Through prize Q&A, consultation and distribution of promotional materials, residents deepened their understanding of hypertension and healthy lifestyle, and how to prevent and treat hypertension, prevent and treat diseases. This understanding has been well received by the residents at the site, has achieved good social effects, and achieved the expected purpose.
By promoting core knowledge such as "healthy weight and healthy blood pressure", "reasonable diet and moderate exercise", "early screening and detection of high-risk individuals", the general public has deepened their understanding of the prevention and treatment of hypertension. , achieve the purpose of early diagnosis and early treatment, thereby reducing the incidence and mortality of cardiovascular and cerebrovascular diseases, making the general public understand the knowledge of prevention and treatment of hypertension, disseminating the concept of healthy lifestyle, preventing hypertension, and improving residents’ initiative in learning health knowledge. , constantly improving residents’ awareness and ability to prevent and control hypertension will surely play a positive role.
Summary of Hypertension Activities 9
In accordance with the requirements of the "Notice of the Municipal and District Health Bureau on Carrying out Publicity Activities for National Hypertension Day and World Mental Health Day", the district took active actions and urgently Focusing on the theme, all street offices and towns (townships) were organized to jointly carry out various publicity activities with rich content. The activities are summarized as follows.
1. Departments attach great importance to and lead on-site command
The District Health Bureau formulated an implementation plan for the entire district based on the requirements of superior departments, put forward overall requirements for the implementation of activities, and made carefully arranged. In accordance with the overall requirements of the Health Bureau, the District Center for Disease Control and Prevention formulated the "Implementation Plan for the District's "Hypertension Day" Activities", which technically ensured the successful completion of this theme day publicity activity.
2. Multi-department cooperation, outstanding publicity effect
On the morning of October 10, under the unified arrangement of the District Health Bureau, the District Center for Disease Control and Prevention jointly organized the Renai and Ping An Community Health Service Centers ***20 health education and publicity personnel and hypertension prevention and control experts launched a large-scale publicity campaign around the theme of this year's National Hypertension Day at the Peach Blossom Fairy Central Square in Longquan, pushing the district's publicity activities to a climax. One theme slogan was hung at the event site, 5 exhibition boards were placed, more than 3,000 copies of various promotional materials focusing on the prevention and treatment of hypertension were distributed, 500 shopping bags were provided, blood pressure was measured for 400 people for free, and health knowledge lectures were provided to more than 500 people. and consulting services. Longquan Radio and Television Station also reported the entire promotional event.
3. Publicity situation of other medical institutions
All types of medical institutions at all levels in the district, under the leadership of the District Health Bureau and the guidance of the District Center for Disease Control and Prevention, combined with the actual situation of the unit Various publicity activities that are colorful and easy for the masses to accept have been carried out. Publicity activities are carried out by hanging themed slogans, posting posters, changing promotional columns, setting up health promotion stations, providing consultations for passing people, measuring blood pressure, and distributing leaflets and foldouts.
According to statistics, all units in the district set up 10 stalls, dispatched more than 20 promotional vehicles, and dispatched publicity personnel and hypertension prevention and treatment experts in this year’s National Hypertension Theme Day promotion activities. Nearly 50 people, more than 9,000 people received education, free blood pressure measurement for xx people, blood sugar measurement for 500 people, distribution of more than xx publicity materials on various chronic disease prevention and treatment, 1,000 promotional gifts, 40 promotional display boards, and hanging themed promotional slogans 30 pieces. Introduction to the causes of hypertension health education
Hypertension is a clinical syndrome characterized by elevated systemic arterial systolic blood pressure (SBP) and/or diastolic blood pressure (DBP). It is currently a clinical syndrome One of the most common and important cardiovascular diseases. Factors of the onset of hypertension: It is currently believed that the onset of hypertension is related to the following factors: 1. Nervous factors: Sympathetic nerves play a leading role in the short-term regulation of hypertension, but they also play a role in the long-term regulation of hypertension.
The main feature is an increase in total peripheral resistance. What role does the sympathetic nerve play in this process? Current research believes that the sympathetic nerve is involved in the occurrence of essential hypertension, but it may not play an important role in the maintenance of hypertension. The causes of increased sympathetic nerve tone are currently believed to be related to the following external factors: ① central ischemic response; ② high-salt diet causes the anterior hypothalamus to inhibit the hypothalamic pressurized area, weakening reflexes and causing increased sympathetic nerve tone; ③ Reaction to stress stimulation: Emotions such as long-term stress, depression, etc., can act on the vasomotor center and cause enhanced sympathetic nerve reactivity. Increased sympathetic tone mainly causes an increase in blood pressure through the following mechanisms: ① Exciting cardiac B1 receptors to increase cardiac output; ② Exciting peripheral vascular α receptors to increase peripheral vascular resistance; ③ Reducing renal blood flow by constricting renal arterioles and activating RAAS ;④ Raise blood pressure by stimulating the adrenal medulla to release epinephrine and norepinephrine
2 Humoral factors (1) Renin-angiotensin system (RAS): RAS consists of a series of peptide hormones and Its corresponding enzyme composition is very important for regulating human blood pressure, water and electrolytes and maintaining the stability of the volume environment. Among them, angiotensin II (AngII) has the most significant effect. It is the hormone with the strongest effect among known endogenous blood pressure substances. Recent studies have found that RAS not only exists in the blood circulation (circulating RAS), but also in the human body. Some tissues and organs (such as kidneys, adrenal glands, heart, blood vessels, walls, brain, etc.) also have RAS (tissue RAS). Further research has also confirmed that high renin-type hypertension is related to increased circulatory activity in the onset of hypertension. In addition to normal renin and low renin hypertension being related to aldosterone increasing water and sodium storage, tissue RAS also plays an important role. The fact that angiotensin-converting enzyme inhibitors (ACEI), which have been used clinically in recent years, are not only effective in the treatment of high renin type but also in the treatment of low renin type hypertension also confirms the above theory. Of course, the relationship between circulating RAS and tissue RAS is quite complicated, and their roles in the pathogenesis of hypertension are still unclear and await future research.
(2) Insulin resistance: Insulin resistance refers to a phenomenon in which the biological effect caused by the normal concentration of insulin in the blood circulation in the body is lower than normal. There are many reasons that can cause insulin resistance, including pre-receptor defects ( Such as abnormalities in the molecular structure of insulin, incomplete transformation of proinsulin into insulin, the presence of insulin-resistant substances in the blood circulation, etc.), receptor level defects (such as reduced number of insulin receptors, decreased receptor affinity, etc.), and post-receptor defects (such as obesity, diabetes In recent years, Uremia et al. have discovered that insulin resistance is common in patients with hypertension (especially essential hypertension), and found that insulin resistance already exists before blood pressure continues to rise or in the early stages of hypertension. Fasting insulin in patients with borderline hypertension. The level is also significantly higher than that of people with normal blood pressure, thus inferring that insulin resistance is related to the onset of hypertension, but the exact mechanism is still unclear.
(3) Atrial natriuretic peptide (ANP): ANP is produced by the atria. A polypeptide hormone synthesized, stored and secreted by muscle cells. It has powerful natriuretic, vasodilatory and blood pressure-reducing effects against RAS and vasopressin. Hypertensive patients are often accompanied by a decrease in ANP response, which may be related to long-term stimulation of hypertension. Increased ANP release is related to the downregulation of ANP receptors (reduced number of ANP receptors and reduced affinity for ANP).
(4) Endothelin (ET): ET is synthesized by vascular endothelial cells. A vasoactive polypeptide that has extensive regulatory effects on cardiovascular, lung, renal, endocrine and nervous system functions. ET can cause strong and lasting contraction of arteries, veins and capillaries. This effect does not depend on the existence of endothelial cells, nor is it affected by a and p. The effects of receptor blockers, but can be reversed by isoproterenol and nitroglycerin; ET can also enhance myocardial contractility; reduce renal blood flow by constricting renal arteries and activate RAAS. The above-mentioned ET vasoconstrictor inotropic renal effects and activation RAAS is the main cause of hypertension.
(5) Vasopressin (VP): VP is a neuropeptide secreted by neurons in the supraoptic nucleus and paraventricular nucleus of the hypothalamus because of its chemical properties. It is also called antidiuretic hormone because of its antidiuretic effect. In addition, VP also plays a certain role in maintaining normal blood pressure homeostasis and vascular tone. Recent studies have shown that VP regulates blood pressure mainly through its effect on the cardiovascular motor center. (Especially essential hypertension), patients often have elevated plasma VP concentrations.
3 Vascular endothelial cell function Vascular endothelial cells play an important role in regulating vascular tone and platelet function. Endothelial cells can produce some vasodilator factors, such as prostacyclin (PGI2), endothelial relaxing factor (EDRF), etc. , can also generate several contractile factors, such as the above-mentioned ETAugII thromboxane A2 (TXA2). Under physiological conditions, the two types of factors interact, but the relaxation factor is slightly dominant, thus inhibiting excessive vasoconstriction and platelet activation, and having a protective effect on circulation. During aging or some disease states, the effect of contractile factors is enhanced (the release of contractile factors increases and the reactivity of blood vessels to contractile factors also increases), leading to an increase in peripheral vascular resistance and hypertension, mainly an increase in diastolic blood pressure.
4 The results of the epidemiological survey on genetic factors show that: 59% of patients with essential hypertension have a family history; the blood pressure levels of monozygotic twins are closer than those of dizygotic twins; adopted children are more closely related to their adoptive parents and There is no correlation between blood pressure between siblings; the prevalence of hypertension in children of parents with normal blood pressure is 3.1%, and the prevalence of hypertension in children of children with one parent suffering from hypertension is 28.3%; both parents suffer from hypertension. The prevalence rate of children with hypertension can reach 45.5%; it can be seen that genetic factors play an important role in the incidence of hypertension. However, the specific inheritance mode and genetic rules have not yet been determined. Most scholars believe that essential hypertension is the result of the simultaneous influence of genetic susceptibility and environmental effects, that is, the genetic predisposition to hypertension and environmental effects are necessary conditions for the occurrence of hypertension. According to current research on the genetic defects of hypertension, Mainly manifested in several aspects such as cell membrane cation (Na+K+Ca2+) transport defects, sympathetic nerve and its mediator metabolism defects, kidney and related factor secretion disorders, and platelet genetic defects.
5 Others such as proto-oncogenes: expression gates cause myocardial and blood vessel wall thickening in people with immune dysfunction, oral contraceptives (increase blood volume by activating RAAS), elderly people with arteriosclerosis (can cause simple systolic hypertension ), etc.
In short, the occurrence of hypertension is a very complex process involving many aspects such as genetic defects in neurohumoral endothelial cell function. Increase (resistance vasoconstriction) - causing hypertension mainly with an increase in diastolic blood pressure; ② Increase in cardiac output (increased heart rate and enhanced myocardial contractility) - causing hypertension mainly with an increase in systolic blood pressure; ③ Blood volume Increase or blood effect consistency