Once, due to the imperfect public health system, nonstandard blood transfusion, unsafe injection and other related reasons, the infection rate of hepatitis B among people born in the 1960s and 1980s was very high. ..
Previous studies have shown that during the period of 1957- 1989, the probability of hepatitis B infection in China reached an unprecedented14%; Even in the popularization of hepatitis B vaccine today.
There are still about 654.38 billion hepatitis B patients in China. Because there is no cure for hepatitis B at present, the evolved chronic hepatitis may greatly increase the incidence of liver cancer and seriously affect the overall health of our people. This is also the haze that China has been facing for decades.
Our country has invested countless money and manpower to try to save it, but there is really nothing we can do for those patients who have been infected with hepatitis B.
But after so many years of efforts, it has dropped from red (> 8%) to about 6%, but our country is still the country with the largest number of hepatitis B patients in the world.
So that every one of us in China is horrified at the mention of "Big Three Yang" and "Little Three Yang", and people's understanding of diseases is always more inclined to "cure".
However, in the medical field, prevention is always the most cost-effective way. I hope everyone will always remember that China is a "hepatitis B country".
Always remind yourself of the importance of preventing diseases. Those who clamor not to get vaccinated, or those who don't get vaccinated because of the vaccine incident, are either stupid or bad.
And, of course, drug-induced liver injury (DILI). In fact, drug-induced liver injury is not a rare disease in the world. It is one of the main side effects caused by western medicine itself, and it is also a reason for the failure of most modern drug clinical trials.
However, liver injury caused by traditional Chinese medicine is a unique disease in China. Most importantly, its harm is far underestimated.
Moreover, it was not until recent years or so that Chinese scholars began to pay attention to this research. The report of liver cancer caused by aristolochic acid published in Science Translation Medicine in recent years is only the beginning of uncovering the hepatotoxicity of traditional Chinese medicine.
According to this article, 78% of liver cancers in Taiwan Province Province and 47% in Chinese mainland are related to aristolochic acid and its derivatives. Although the exact number is still controversial, the role of aristolochic acid in the formation of liver cancer is still unknown.
But the damage of aristolochic acid and its derivatives to liver cells really exists. If taking some traditional Chinese medicines for a long time may lead to liver cancer, people and regulatory authorities have paid attention to it. The drug-induced liver injury caused by traditional Chinese medicines is more acute and more difficult to identify.
At the beginning of 20 19, a paper published by Shanghai jiaotong university in gastroenterology began to systematically evaluate the drug-induced liver injury caused by traditional Chinese medicine on a large scale.
From 20 12 to 20 14, nearly 26,000 cases of drug-induced liver injury in 308 medical institutions were counted. It was found that drug-induced liver injury caused by traditional Chinese medicine or health care products accounted for 26.8 1% of all DILI cases, which was higher than that caused by anti-tuberculosis drugs (2 1.99%).
If we make a distinction between liver injury and diseases, we may find that 40.3% of DILI in patients with skin diseases and senile diseases is caused by traditional Chinese medicine.
In fact, this disease is not entirely unique to China. The whole Asian region radiated by China culture, including South Korea, Japan and Singapore, is the hardest hit area of drug-induced liver injury caused by traditional Chinese medicine and herbs. However, we want to emphasize that the liver injury caused by traditional Chinese medicine is far underestimated in China.
Supporters of traditional Chinese medicine claim that "only" 26.8% of Dili is caused by traditional Chinese medicine and health care products, and the rest 70% is mostly western medicine, so traditional Chinese medicine is safer than western medicine.
However, the hepatotoxicity of western medicine has been widely studied and can be expected. The hepatotoxicity of traditional Chinese medicine includes notoginseng, tripterygium wilfordii, astragalus, mugwort leaf, ginkgo leaf, Polygonum Multiflori Radix, Psoralea corylifolia, Rhizoma Corydalis, rhubarb, cassia seed, aconite root and so on. , has been reported.
However, its toxicology research is relatively scarce, and its composition is complex, combining Chinese and western. There are many avoidable liver injuries caused by traditional Chinese medicine every day. In addition, kidney injury caused by traditional Chinese medicine may also be one of the endemic diseases in China.
The word "a man and a half woman" is often used to describe people who have no children or few children after marriage. For example, "I have been married f