Base complementary pairing refers to the phenomenon that the bases of nucleotide residues in nucleic acid molecules are connected with each other through hydrogen bonds according to the corresponding relationship between A and T, A and U, G and C, which was first proposed by Watson and Crick in the DNA double helix structure model. Later, it was found that this rule not only existed in DNA replication, but also in reverse.

The relationship between DNA and RNA in the recording process also has a similar law.

Even all bases in single-stranded RNA that are close in space and can be combined with each other through hydrogen bonds can be paired in this way. Therefore, this principle has extremely important biological significance. The basic biological processes of genetic information transmission, such as replication, transcription, reverse transcription and translation, follow this principle.

Even all bases in single-stranded RNA that are close in space and can be combined with each other through hydrogen bonds can be paired in this way. Therefore, this principle has extremely important biological significance. The basic biological processes of genetic information transmission, such as replication, transcription, reverse transcription and translation, follow this principle.