Pregnant mothers should not be ignored and should be examined in detail. The main reason why people in China suffer from liver cancer is that hepatitis B is often infected vertically by their mothers at birth, and there is a 50% chance that mother B will infect the fetus vertically during pregnancy and delivery. Therefore, the defense of hepatitis B should start from the mother. Recently, the news reported that the artist An Juncan died of liver cancer, which made people feel very sorry. So young, 3 1 year old died of liver cancer. Why does liver cancer happen to people aged 30? How to prevent it? Studies have pointed out that the main cause of liver cancer in China is that hepatitis B is mostly infected vertically by the mother at birth. Mother B has a 50% chance of vertically infecting the fetus during pregnancy and childbirth, and the earlier she gets hepatitis B, the easier it is to get liver cancer. It is said that An Juncan was born with hepatitis B, and his drinking and abnormal work and rest led to the early occurrence of liver cancer.

Taiwan Province province began to implement neonatal vaccination and immunoglobulin injection as early as 1984. But there is still a failure rate of 5% to 15%. These children who have failed vaccination (such as An Juncan) are prone to develop chronic hepatitis and become chronic carriers in their adult life, which has become a corner of prevention in family life and public health. If you have an unhealthy lifestyle as an adult, you are more likely to become liver cirrhosis or liver cancer. So the defense against hepatitis B should start with your mother.

Hepatitis B patients are more likely to get liver cancer than normal people, and the probability of liver cancer in hepatitis B patients is 100 to 150 times higher than normal people. Among patients with liver cancer, hepatitis B carriers account for 60% and hepatitis C accounts for 30%. Therefore, prevention of liver cancer should be the first line. At present, nearly 3 million carriers in Taiwan Province Province should pay attention to follow-up. If hepatitis B carriers have poor liver function and high viral load, they are more likely to get liver cancer. The existing formula can calculate the probability of cancer.

The 27-year-old pregnant mother drew blood for the first time at 12 weeks of pregnancy, and found that hepatitis B carriers and E antigen were positive (high finger representing hepatitis B infection). She nervously asked herself if she would get liver cancer. Will it infect others and children? Can I use antiviral drugs during pregnancy?

In the above cases, the 27-year-old pregnant mother is only a carrier, with normal liver function and low virus amount. When she is followed up for 3 to 6 months, if the virus is high, she will consider using antiviral drugs. But pregnancy is also a dangerous period for the increase of virus quantity. Therefore, pregnant mothers with hepatitis B must track the virus amount and liver function index of E antigen, and also pay attention to whether there is hepatosplenomegaly in clinic.

Anti-hepatitis B, mainly oral antiviral drugs. Clinically, the effect and safety of antiviral drugs used by pregnant women with double positive hepatitis B (HBsAg and HBeAg are both positive) and the virus amount is higher than HBV DNA > 107 COPIES/ml/ml were preliminarily experienced. At present, among the drugs used, sibufitivudine and levator tenofovir are Class B drugs which are safe for pregnancy, while Gannerlamivudine is Class C, which is the first antiviral drug.

Because of the limitations and side effects of interferon therapy, oral antiviral drugs are still the main means of clinical treatment. At present, the oral drugs are lamivudine, adefovir, entecavir and telbivudine, among which lamivudine accounts for 90% of the total, followed by adefovir 39.7% and entecavir 20.6%, and Gananer and Gananer are conditional payments for health insurance. At present, Fu Bi in Bayloc and Xi need to be purchased at their own expense.

After 28 weeks of pregnancy, the use of hiberfutidine and canon lamivudine can significantly reduce the amount of maternal virus and the probability of fetal infection. Even if three drugs are used, the impact on the fetus is very slight. Therefore, hepatitis B carriers, high-risk groups and pregnant mothers with high virus concentration should consider continuous medication under the supervision of doctors. As for patients, which one is better? At present, it is generally believed that telbivudine and tenofovir are better than lamivudine.

Double-positive mothers (both HBsAg and HBeAg are positive) and pregnant women with virus concentration higher than (107COPIES/ml) are the high-risk groups of vertical mother-to-child infection. If pregnant mothers in high-risk groups undergo amniocentesis or give birth naturally, it is also easy to infect the fetus. Therefore, it is suggested that pregnant mothers in high-risk groups of hepatitis B choose aseptic caesarean section for delivery. Breast milk contains less virus, so breast-feeding is no problem.