It refers to an ideological emancipation movement that rose in Europe from14th century to16th century. Its slogan is to revive the ancient Greek and Roman culture, with the aim of destroying the feudal thought centered on God and establishing a new bourgeois thinking and culture centered on people. Its ideological core is humanism.
Humanism is: advocating human nature and opposing abstinence.
Advocate human rights and oppose theocracy.
Advocate rationality and oppose ignorance.
Advocate unity and oppose separatism.
Used in the matrix, it probably means liberating human beings and destroying the matrix.