185 1 year, Ernest Christie Frederic Schering began to manufacture and sell drugs in Berlin. Three years later, Schering opened its first production workshop.

189 1 year, Merck entered the United States, and its parent company, E. Merck, was established in Tate, Daams on 1668.

1899, the first edition of Merck's Handbook of Diagnosis and Treatment was distributed to doctors and pharmacists. Today, Merck's Diagnostic and Therapeutic Manual has been published in 17 languages.

1933, Merck established its first laboratory in Lowe, New Jersey.

1944, Merck researchers cooperated with Rutgers University and discovered streptomycin. In the same year, Merck successfully synthesized cortisone.

1953, Merck and Sharp &; The merged Dohme company is called Merck in the United States and Canada, and MSD in other regions.

1955, Schering-Plough's team of scientists successfully converted cortisone into prednisone, which became one of the most outstanding medical advances in the middle of the 20th century.

1955, Schering-Plough Foundation was established. Two years later, the Merck Foundation was established.

1963, Merck introduced the first dose of measles vaccine and mumps vaccine four years later. The latter was developed by Dr. Morris Hillman from the throat culture of his daughter Jerry Lynn.

197 1 year, Xianling Company merged with Baoya Company to form Xianling Baoya Company. In 2007, Schering-Plough merged with Organon Biotechnology Company in the Netherlands.

In 2000, Merck and Schering-Plough established a joint venture in the United States to develop and sell new prescription drugs for lowering cholesterol and treating respiratory diseases.

In 2009, Merck and Schering-Plough merged to become the world's leading medical company, dedicated to making the world a better place.