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Is the hangover medicine useful?
In recent years, there have been some self-proclaimed people in the Jianghu. A thousand cups are not drunk! ? Is it? Brother, 4 kg? Brother, 5 kg? With what? Brother 6 Jin? .

In recent years, all parts of the country have been cracking down on drunk driving, because many people have been jailed for drunk driving. Some people are worried about being investigated for drinking too much? Drunk driving? Some people are afraid of getting hurt after drinking too much, so they start to think of ways. All kinds of statements are ok? Accelerate hangover and protect the liver? Anti-hangover drugs appeared quietly.

antialcoholic drug

Search on the Internet? Anti-hangover drugs? After that, all kinds of titles are? Are you drunk? 、? Jiubao? 、? Wine lovers? Links to various related products will come to you. Click on one of them called. Wine ganoderma lucidum? The web page of the product, which reads impressively? Drinking is harmless, driving is not penalized? 、? 20 minutes to enhance alcohol consumption, thousands of glasses are not drunk? The slogan is particularly eye-catching, so the question is, do these hangover drugs really have such magical effects? If so, how did it appear on the Internet before? Brother, 4 kg? 、? Brother, 5 kg? With what? Brother 6 Jin? Have you all taken these magic medicines?

Brother 6 Jin?

There are many kinds of anti-hangover drugs, mainly in the form of tablets, capsules, oral liquid and so on; The ingredients of the product are also varied, from pueraria lobata, Lycium barbarum and Ganoderma lucidum to protein powder, amino acids, vitamins and calcium pantothenate? Anti-hangover drugs? ; Prices range from tens to hundreds of yuan.

What about these? Anti-hangover drugs? Can you wake up or not?

From a medical point of view, there is no real hangover cure. The body metabolizes alcohol mainly through the liver, skin and respiratory system, among which the liver is the most important? Everyone knows that drinking hurts the liver. After alcohol enters the human body, alcohol dehydrogenase is responsible for oxidizing alcohol into acetaldehyde, which is the first step of the whole reaction. Acetaldehyde can make people drunk, so we must quickly convert these acetaldehyde into something else. At this time, acetaldehyde dehydrogenase in the liver will oxidize acetaldehyde into acetic acid (some people will blush after drinking, which is the defect of acetaldehyde dehydrogenase. This person's gene is a little abnormal, and there is too little acetaldehyde dehydrogenase in the liver, which leads to too much acetaldehyde accumulation. Acetaldehyde is much more toxic than ethanol, and a little bit can make people drunk again, showing blushing and dizziness. So you see, in order not to get drunk, the liver needs to produce a lot of acetaldehyde dehydrogenase to oxidize acetaldehyde? This process is a slow biochemical reaction, which cannot be completed quickly in the human body.

From this biochemical mechanism, how is the market? Anti-hangover drugs? Does not include this itself? Acetaldehyde dehydrogenase? Even if? Not even with enzymes? The enzyme is protein, which will be digested after eating, and it can't continue to play the role of hangover. So when alcohol enters the blood circulation, it is difficult to reduce the alcohol content in a short time. At present, in clinic, in order to alleviate the serious symptoms of drunkenness, intravenous injection of glucose or physiological saline is generally used.

Some readers may ask, can I eat? Anti-hangover drugs? And produce it in the liver? Acetaldehyde dehydrogenase? And then what? There is no relevant literature on this point, because human metabolism is a very complicated process, and it is necessary to further explore the pharmacokinetics of this part by combining liquid chromatography and mass spectrometry (generally speaking, enzymes are often the target of drugs, but only enzyme inhibitors are used in drugs that act on enzymes? This medicine reduces the action of enzymes; There is no statement that there is an enzyme promoter in pharmacology. Under the suitable temperature and pH value in the body, the enzyme has the greatest ability. We may not be able to increase the ability of enzymes in the body by taking medicine. Many pharmaceutical companies claim that products that can increase the ability of acetaldehyde dehydrogenase fail to submit experimental reports.

Therefore, the consumption of alcohol is determined by the amount of alcohol dehydrogenase and acetaldehyde dehydrogenase in the body. The amount of these two enzymes is innate, and there is no means to increase the secretion of these two enzymes at present.

? There is no real panacea for hangovers! ? Shang Jia, chief physician of the Department of Infectious Diseases of Henan Provincial People's Hospital, said, What is on the market? Anti-hangover drugs? No matter Chinese medicine or western medicine, there is no complete hangover effect.

For some people who really have to drink because of work, entertainment and other reasons, you can remember some small ways to avoid getting drunk. For example, drinking yogurt or milk half an hour before drinking can protect the gastric mucosa; Eating a little staple food at the dinner table can also play a protective role; And don't drink fast wine, otherwise it will increase the burden on the liver; Drink plenty of water after drinking and eat some fruits with diuretic effect.

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Author: Tadpole Jun