From Lovecraft's "Supernatural Horror in Literature" in 1927

The oldest and strongest human emotion is fear; the oldest and strongest fear originates from From the unknown... A real horror story should not just be about murders, bones, ghosts... An unknown fear that cannot be explained and originates from outside human common sense must exist... violate and break all natural rules because of these "everyday ironclads" "Law" is the only remaining line of defense between mankind and the unknown evil in the unfathomable starry sky.

What echoes this passage is the beginning of the masterpiece of the Cthulhu mythology, "Call of Cthulhu", so it might as well be placed here

... There is nothing merciful than man's inability to comprehend all the knowledge he possesses.

We live on an island called ignorance surrounded by a sea of ??darkness, but this does not mean that we should set sail and explore unknown areas... If one day humans can understand the truth of the universe and our insignificance in it Status will definitely plunge everyone into eternal madness...