Everyone knows the greatness of a mother, and knows that "it's ungrateful for parents not to raise children". At home, most people still believe that the reward given by children to their mothers is the care and filial piety for their mothers, which requires a long wait and hard work. However, recent scientific research shows that people have rewarded their mothers when they are in the fetus, and he will give them some mysterious gifts. Some fetal cells will magically penetrate the placental barrier into the mother and stay in the mother for a long time, playing a wonderful role in repairing maternal damage and inhibiting tumors.
The scientific community has confirmed that there are children's cells in maternal blood and organs, and these cells are found in maternal spleen, liver, lung, kidney, brain, bone marrow, thyroid gland and skin.
The cells "migrated" from the fetus to the mother are not mature cells, but are similar to stem cells. Generally speaking, it is like a "baby cell". When it enters the mother's body, it has not yet decided what it will eventually become, so it has the ability to form any kind of cells in the mother's body. Medically, it is called "primordial cell related to pregnancy" and "fetal microchimerism" in the mother. It maintains the ability of differentiation and replication in the mother body, which is undoubtedly a great wealth for the medical community, because it can become heart cells, liver, blood, muscle or brain cells to repair the damage and pathological changes in the mother body.
At present, such cells found in the mother body include hematopoietic stem cells, epithelial primordial cells, placenta-derived stem cells, cytotrophoblasts and mesenchymal stem cells. These fetal cells play a positive role in the following diseases of the mother:
1. Breast cancer
Epidemiological statistics show that the probability of breast cancer in pregnant women is significantly lower than that in childless women. At that time, it was speculated that it was related to breastfeeding, but the recent research report published in the journal Cancer Research expounded a new point of view. Researchers from the University of Washington and Fred hutcheson Research Center surveyed 82 women who had given birth to boys, and 35 of them were diagnosed with breast cancer. By comparing the samples of male fetal deoxyribonucleic acid (DNA) in maternal blood, the researchers found that 14% of breast cancer patients had male fetal DNA in their blood, while 43% of women without breast cancer had it.
Because male fetuses contain XY chromosomes, their DNA is easier to separate than that of female fetuses with XX chromosomes, so this survey only takes pregnant women who have given birth to male fetuses as research objects. "My hypothesis is that fetal cells may recognize the embryonic form of breast cancer cells in the mother's body and kill the cancer cells before they start to move," said research leader V·K· Gardi.
II. Rheumatism
There is a saying among the people in China that "having children for illness" means that rheumatic joint pain can be alleviated or cured after pregnancy. Fifteen years ago, the Nobel Prize winner and American scientist Hench found that when the baby's human leukocyte antigen is very different from the mother's cells, the rheumatoid disease of pregnant women will be alleviated; The higher the proportion of fetal microchimerism, the more obvious the symptom relief of pregnant women with rheumatoid diseases.
III. Cerebrovascular and nervous system diseases
Through experiments on mice, the researchers found that the "fetal microchimerism" in the pregnant mice can cross the placental barrier, enter the blood, and finally reach the maternal brain. After breaking through an almost airtight biological wall-the blood-brain barrier, they bring information into the brain and complete their mission of repairing cells.
Adult nerve cells cannot be regenerated once they are damaged, but these fetal cells can differentiate into nerve cells and proliferate in the mother's brain to repair these injuries that cannot be repaired by adults themselves. If this discovery is verified in humans, it will be of strategic significance for the treatment of various embolisms or some nervous system decline diseases, such as Alzheimer's disease and Parkinson's disease.
IV. Skin damage
Scientists found one of a large number of fetal microchimerism in the skin damage of mice, epithelial primordial cells, and found that this cell is closely related to the repair of maternal skin damage, especially the angiogenesis.
V. Chemical damage to the liver
In the journal of Human Reproduction in 27, it was reported that a large number of fetal cells were found in the liver of a pregnant mouse model with chemical liver damage, and the number at the eighth week of pregnancy was significantly higher than that at the fourth week of pregnancy, and persisted in the liver after delivery, and the storage and migration of fetal cells in the spleen were also found.
In 24, the American Journal of Laboratory Observation wrote that the detection rates of fetal cells were 43%, 25% and 33% respectively through liver biopsy of 14 patients with liver cirrhosis, 8 patients with hepatitis C and 6 patients with other liver diseases who had given birth to boys. This shows that fetal cells can migrate to the damaged part of the mother in vivo.
VI. Lung Cancer
In 26, an article in the American Journal of Obstetrics and Gynecology pointed out that on the tissue sections of six mothers whose lungs were partially removed due to lung cancer, fetal cells were found to form a protective wall around the diseased tissues, which limited the expansion of tumor cells, and it was speculated that these cells were usually hidden in the mother's bone marrow and other tissues.
The mouse experiment showed that fetal cells could be detected in maternal blood at 1-12 days of pregnancy, appeared in organs at 13 days, increased obviously at 16 days, and gradually subsided after delivery, and no fetal cells were detected in peripheral blood at 3 weeks after delivery. However, after the third pregnancy, 4% of the mothers can keep fetal cells in the blood for a long time.
Scientists have first detected fetal cells from pregnant women's blood on the 33rd day of pregnancy, and this technology has been applied to prenatal diagnosis. More interestingly, the number of fetal cells detected in mothers with a history of natural or induced abortion is 2.4 times that of normal pregnant mothers.
Although a life has passed, he left his cells in his mother's body, leaving traces of his life. How long will this trace remain? The author thinks: Our former children will accompany us all our lives-because scientists have detected the cells of her 51-year-old son in the bone marrow of a mother's ribs.
Of course, "fetal microchimerism" is a double-edged sword, which can cause some autoimmune diseases of the mother in a few cases, but it plays a long-term and loyal role in protecting the mother and repairing organ damage in most mothers. And how do these fetal cells escape the maternal immune mechanism and stay in the mother for a long time? It is still an unsolved mystery.
We also know that pregnancy can alleviate or even cure some diseases, such as lupus erythematosus, psoriasis, multiple sclerosis, dysmenorrhea, gastroptosis, endometriosis, migraine, etc. Whether these magical phenomena are related to the mysterious gift-fetal microchimerism needs further scientific research and confirmation.
But in any case, we have to sigh: creation is so magical, it makes the bond of love between mother and child so close, and it is really "you have me, and I have you." Whether mentally or physically, children are a precious gift given to their mothers by life!