They all know each other. Neiguang clan and Qianshou clan are sworn enemies. As Ban said, as long as a country hires either of the two families, the other country at war with it will immediately hire the other, but the two families jointly created Konoha, so the first generation of Huo Ying-Senju Hashirama and Uchibo Madara can be regarded as great friends. Later, because of the influence of the Thousand-Handed Clan and the Neiguang Clan, they finally met.

As for Senju Tobirama, Senju Hashirama's younger brother and Uchiha Izuna's younger brother, they should have a good relationship. In addition, there is a CP with a column in Huo Ying. From this point of view, four people ... should be familiar with each other.