This disease is known and understood by people because of a challenge. Stephen Hawking, a famous physicist, has been suffering from gradual freezing for more than 50 years. The female doctor of Peking University also lost her athletic ability because of the gradual freezing of people. The patient with gradual freezing is very painful. Do you know how they feel?
Frostbite is also called amyotrophic lateral sclerosis (ALS). Patients with this disease will gradually lose their mobility, and then they can't communicate, breathe or eat. However, in the process of their physical deterioration, their thinking, thoughts and emotions are normal, which is the pain of patients with gradual freezing.
What does it feel like to freeze gradually?
A person's thinking is just like a normal person, even sharper than usual. The external high-level cognition is normal, and there are high-level emotions. In short, their thinking is normal and they are smarter. But this soul is imprisoned in a motionless body, just like a hostage in an iron cage. You know everything about the outside world, but you can't stand, move or control your body. Mickey and Murray Tuesday: "It's like a monster frozen to a pulp in a science fiction movie."
What is gradual freezing?
It is precisely because of the damage of upper and lower motor neurons that some muscles, limbs, trunk, chest and abdomen muscles dominated by the medulla oblongata gradually weaken and atrophy, and then dysphagia and speech difficulties occur, and finally dyspnea leads to respiratory failure. The etiology is not clear, and it may be related to heredity or genetic defects. As Yang li Ping said, God gave the peacock beauty, but he didn't give him a beautiful voice. Gradually frozen people are more acute than ordinary people, so they can't move their limbs.
However, in addition to congenital factors, environmental factors can also lead to the onset, such as heavy metal aluminum poisoning can cause neuromotor injury. At present, it is believed that the causes of nerve injury are as follows:
1. neurotoxic substances accumulate, and glutamic acid accumulates between nerve cells, causing nerve cell damage.
2. Free radicals destroy nerve cell membranes.
3. Without nerve growth factor, nerve cells can't continue to grow and develop.
The father of a female doctor of Peking University suffering from gradual freezing was not in a good mental state when interviewed. He leaned back in his chair and said that he often felt dizzy and weak, and he suspected that he and his daughter had the same disease. What are the symptoms of freezing people?
In the early stage, patients will feel weak, occasionally their muscles will beat and they will be tired easily. These symptoms are easily confused with other diseases. Will gradually develop into muscle atrophy, dysphagia, and finally unable to breathe spontaneously, relying on a ventilator.
What tests do you need to do to diagnose a frozen person?
In addition to the clinical examination in neurology, electromyography, nerve conduction velocity detection, serum specific antibody examination, lumbar puncture cerebrospinal fluid examination, imaging examination, and even muscle biopsy should be done to diagnose gradual freezing. Electromyography is a very important part of it. Although this examination may make the patient feel uncomfortable, it must be done. It is mainly used to measure the electrical activity of some muscles.
I hope that after reading this article, everyone can understand the pain of patients with gradual freezing. You can also remember this Anthony who "tirelessly hopes to arouse the world's attention to the gradual freezing of human diseases and is directly responsible for promoting the world-famous ice bucket challenge"!
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