Hyperthermia is to raise the patient's body temperature to 40℃ ~ 42℃ and artificially create a "hot" environment for the human body. In this temperature environment, cancer cells that are afraid of "heat" will be directly killed by high fever and apoptosis. Cancer cells that can't be removed by conventional means such as surgery or can't be found by existing means are inevitably tracked and killed by whole body hyperthermia combined with adjuvant chemotherapy, although they are hidden after escaping the net. Secondly, whole body hyperthermia can increase the concentration of chemotherapy drugs in tumor tissues, thus enhancing the efficacy of chemotherapy drugs and enhancing the sensitivity of cells to radiotherapy, thus achieving the purpose of enhancing the efficacy of radiotherapy. In addition, whole body hyperthermia can also activate the paralyzed immune system and produce anti-tumor immunity, thus inhibiting and killing metastatic or subclinical lesions.

Another remarkable feature of hyperthermia is that it has no damage to normal cells. Normal tissues have a rich and orderly vascular network, which provides oxygen and nutrients for tissues, and can quickly take away the heat energy generated by metabolism while transporting carbon dioxide and metabolic waste, with high working efficiency and strong heat dissipation ability. However, the vascular network structure of tumor tissue is abnormally distorted, uneven in thickness, and even blocked by tumor thrombus. Heat accumulation is easy to occur after heating, and the temperature is 3℃ ~ 7℃ higher than that of adjacent normal tissues. The tumor cells "honestly" stayed there and were "baked" to death.