In hospitals, prescriptions are signed by doctors, which means that prescriptions need two doctors to sign for samples. The so-called double sign is suitable for narcotic psychotropic drugs used in anesthesiology department and operating room of hospitals. When using these drugs, two people need to sign the agreement, and there is a special person to manage these drugs. The main reason is that this medicine has a special effect and is easy to be addicted. If not properly managed and used, it will cause serious harm to society and individuals. Therefore, a double signature is required.