It is not certain whether the skull symbolizes the breakdow" />
The correct title of Hans Holbein the Younger's Jean de Dinteville and Georges de Selve (`The Ambassadors') is "The Ambassadors"
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http://www.wga.hu/art/h/holbein/hans_y/1535a/1ambassa.jpg
It is not certain whether the skull symbolizes the breakdown of the relationship between the two. This painting The meaning has always been controversial, and there is currently no accurate explanation of the skull.