There is a long historical and cultural background behind this sentence. Wei, Jin, Southern and Northern Dynasties is a very turbulent period in the history of China, and it is also a period of cultural prosperity. During this period, many outstanding figures and cultural achievements emerged, such as the Seven Sages of Bamboo Forest, Tao Yuanming and Wang Xizhi. So it is very important to understand the history and culture of this period.
The phrase "I don't know how to talk about Wei and Jin Dynasties" can also be used to describe that if you don't understand the history and culture of a certain period or a certain field, you can't really understand the characteristics and achievements of this period or field.